Business US 22 was designated along the former US 22 through Monroeville.
When present-day I-376 (Penn-Lincoln Parkway) was built in the 1950s
and early 1960s, US 22 was moved to follow the interstate, and the
business route designation took over. Business US 22 ties into I-376/US
22 at Exit 10B in Churchill and Exit 15 in Monroeville. Locally, the
business route is known as the William Penn Highway along its entire
Eastern End | Western
US 22 takes over the William Penn Highway near here, eastbound at
the end of Business US 22. In the distance are overhead guide signs
on the I-376/US 22 freeway, which meets Business US 22 at its end
off to the right.
Denny Pine 2003
Westbound on US 22 at the interchange with Business US 22 and I-376.
US 22 joins the I-376 Parkway East freeway, while Business US 22 begins
and takes over the old route, the William Penn Highway.
photo (Terraserver/USGS, 1993): The middle interchange is where
Business US 22 (enters from the left) ends at I-376/US 22 (enters
from the upper left). The interchange at the lower right is where
I-376 meets I-76, and the interchange at the upper right is where
I-376/US 22 meets the road to PA 48.